Protective effect of Growth Hormone-Releasing Hormone agonist in bacterial toxin-induced pulmonary barrier dysfunction

Rationale: Antibiotic treatment of patients infected with G(−) or G(+) bacteria promotes release of the toxins lipopolysaccharide (LPS) and pneumolysin (PLY) in their lungs. Growth Hormone-releasing Hormone (GHRH) agonist JI-34 protects human lung microvascular endothelial cells (HL-MVEC), expressin...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Czikora, Istvan, Sridhar, Supriya, Gorshkov, Boris, Alieva, Irina B., Kasa, Anita, Gonzales, Joyce, Potapenko, Olena, Umapathy, Nagavedi S., Pillich, Helena, Rick, Ferenc G., Block, Norman L., Verin, Alexander D., Chakraborty, Trinad, Matthay, Michael A., Schally, Andrew V., Lucas, Rudolf
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2014
Sujets:
Physiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097355/
https://ncbi.nlm.nih.gov/pubmed/25076911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00259
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