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Agonist of growth hormone-releasing hormone reduces pneumolysin-induced pulmonary permeability edema

Aggressive treatment with antibiotics in patients infected with Streptococcus pneumoniae induces release of the bacterial virulence factor pneumolysin (PLY). Days after lungs are sterile, this pore-forming toxin can still induce pulmonary permeability edema in patients, characterized by alveolar/cap...

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Bibliographische Detailangaben
Hauptverfasser: Lucas, Rudolf, Sridhar, Supriya, Rick, Ferenc G., Gorshkov, Boris, Umapathy, Nagavedi S., Yang, Guang, Oseghale, Aluya, Verin, Alexander D., Chakraborty, Trinad, Matthay, Michael A., Zemskov, Evgeny A., White, Richard, Block, Norman L., Schally, Andrew V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277580/
https://ncbi.nlm.nih.gov/pubmed/22308467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121075109
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