Protective effect of Growth Hormone-Releasing Hormone agonist in bacterial toxin-induced pulmonary barrier dysfunction

Rationale: Antibiotic treatment of patients infected with G(−) or G(+) bacteria promotes release of the toxins lipopolysaccharide (LPS) and pneumolysin (PLY) in their lungs. Growth Hormone-releasing Hormone (GHRH) agonist JI-34 protects human lung microvascular endothelial cells (HL-MVEC), expressin...

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Detalhes bibliográficos
Main Authors: Czikora, Istvan, Sridhar, Supriya, Gorshkov, Boris, Alieva, Irina B., Kasa, Anita, Gonzales, Joyce, Potapenko, Olena, Umapathy, Nagavedi S., Pillich, Helena, Rick, Ferenc G., Block, Norman L., Verin, Alexander D., Chakraborty, Trinad, Matthay, Michael A., Schally, Andrew V., Lucas, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097355/
https://ncbi.nlm.nih.gov/pubmed/25076911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00259
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