Protective effect of Growth Hormone-Releasing Hormone agonist in bacterial toxin-induced pulmonary barrier dysfunction

Rationale: Antibiotic treatment of patients infected with G(−) or G(+) bacteria promotes release of the toxins lipopolysaccharide (LPS) and pneumolysin (PLY) in their lungs. Growth Hormone-releasing Hormone (GHRH) agonist JI-34 protects human lung microvascular endothelial cells (HL-MVEC), expressin...

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Dades bibliogràfiques
Autors principals: Czikora, Istvan, Sridhar, Supriya, Gorshkov, Boris, Alieva, Irina B., Kasa, Anita, Gonzales, Joyce, Potapenko, Olena, Umapathy, Nagavedi S., Pillich, Helena, Rick, Ferenc G., Block, Norman L., Verin, Alexander D., Chakraborty, Trinad, Matthay, Michael A., Schally, Andrew V., Lucas, Rudolf
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097355/
https://ncbi.nlm.nih.gov/pubmed/25076911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00259
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