Epithelial Sodium Channel-α Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction

BACKGROUND: Streptococcus pneumoniae is a major etiologic agent of bacterial pneumonia. Autolysis and antibiotic-mediated lysis of pneumococci induce release of the pore-forming toxin, pneumolysin (PLY), their major virulence factor, which is a prominent cause of acute lung injury. PLY inhibits alve...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Czikora, Istvan, Alli, Abdel A., Sridhar, Supriya, Matthay, Michael A., Pillich, Helena, Hudel, Martina, Berisha, Besim, Gorshkov, Boris, Romero, Maritza J., Gonzales, Joyce, Wu, Guangyu, Huo, Yuqing, Su, Yunchao, Verin, Alexander D., Fulton, David, Chakraborty, Trinad, Eaton, Douglas C., Lucas, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519615/
https://ncbi.nlm.nih.gov/pubmed/28785264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00842
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados