Protective effect of Growth Hormone-Releasing Hormone agonist in bacterial toxin-induced pulmonary barrier dysfunction

Rationale: Antibiotic treatment of patients infected with G(−) or G(+) bacteria promotes release of the toxins lipopolysaccharide (LPS) and pneumolysin (PLY) in their lungs. Growth Hormone-releasing Hormone (GHRH) agonist JI-34 protects human lung microvascular endothelial cells (HL-MVEC), expressin...

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Autori principali: Czikora, Istvan, Sridhar, Supriya, Gorshkov, Boris, Alieva, Irina B., Kasa, Anita, Gonzales, Joyce, Potapenko, Olena, Umapathy, Nagavedi S., Pillich, Helena, Rick, Ferenc G., Block, Norman L., Verin, Alexander D., Chakraborty, Trinad, Matthay, Michael A., Schally, Andrew V., Lucas, Rudolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097355/
https://ncbi.nlm.nih.gov/pubmed/25076911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00259
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