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The deadly connection between endoplasmic reticulum, Ca(2+), protein synthesis, and the endoplasmic reticulum stress response in malignant glioma cells
BACKGROUND: The endoplasmic reticulum (ER) is involved in Ca(2+) signaling and protein processing. Accumulation of unfolded proteins following ER Ca(2+) depletion triggers the ER stress response (ERSR), which facilitates protein folding and removal of damaged proteins and can induce cell death. Unfo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096176/ https://ncbi.nlm.nih.gov/pubmed/24569545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou012 |
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