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Inhibition of glioma growth by minocycline is mediated through endoplasmic reticulum stress-induced apoptosis and autophagic cell death

BACKGROUND: We have reported that minocycline (Mino) induced autophagic death in glioma cells. In the present study, we characterize the upstream regulators that control autophagy and switch cell death from autophagic to apoptotic. METHODS: Western blotting and immunofluorescence were used to detect...

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Autors principals: Liu, Wei-Ting, Huang, Chih-Yuan, Lu, I-Chen, Gean, Po-Wu
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748919/
https://ncbi.nlm.nih.gov/pubmed/23787763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not073
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