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Inhibition of glioma growth by minocycline is mediated through endoplasmic reticulum stress-induced apoptosis and autophagic cell death

BACKGROUND: We have reported that minocycline (Mino) induced autophagic death in glioma cells. In the present study, we characterize the upstream regulators that control autophagy and switch cell death from autophagic to apoptotic. METHODS: Western blotting and immunofluorescence were used to detect...

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Detalhes bibliográficos
Main Authors: Liu, Wei-Ting, Huang, Chih-Yuan, Lu, I-Chen, Gean, Po-Wu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748919/
https://ncbi.nlm.nih.gov/pubmed/23787763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not073
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