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Endoplasmic Reticulum Stress Contributes to Gefitinib-Induced Apoptosis in Glioma

Adequate stress on the Endoplasmic Reticulum (ER) with the Unfolded Protein Response (UPR) could maintain glioma malignancy. Uncontrolled ER stress, on the other hand, predisposes an apoptosis-dominant UPR program. We studied here the proapoptotic actions of the Epidermal Growth Factor Receptor (EGF...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chang, Cheng-Yi, Pan, Ping-Ho, Wu, Chih-Cheng, Liao, Su-Lan, Chen, Wen-Ying, Kuan, Yu-Hsiang, Wang, Wen-Yi, Chen, Chun-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069544/
https://ncbi.nlm.nih.gov/pubmed/33920356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083934
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