Endoplasmic Reticulum Stress Contributes to Gefitinib-Induced Apoptosis in Glioma

Adequate stress on the Endoplasmic Reticulum (ER) with the Unfolded Protein Response (UPR) could maintain glioma malignancy. Uncontrolled ER stress, on the other hand, predisposes an apoptosis-dominant UPR program. We studied here the proapoptotic actions of the Epidermal Growth Factor Receptor (EGF...

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Published in:Int J Mol Sci
Main Authors: Chang, Cheng-Yi, Pan, Ping-Ho, Wu, Chih-Cheng, Liao, Su-Lan, Chen, Wen-Ying, Kuan, Yu-Hsiang, Wang, Wen-Yi, Chen, Chun-Jung
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069544/
https://ncbi.nlm.nih.gov/pubmed/33920356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083934
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