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Endoplasmic Reticulum Stress Contributes to Gefitinib-Induced Apoptosis in Glioma

Adequate stress on the Endoplasmic Reticulum (ER) with the Unfolded Protein Response (UPR) could maintain glioma malignancy. Uncontrolled ER stress, on the other hand, predisposes an apoptosis-dominant UPR program. We studied here the proapoptotic actions of the Epidermal Growth Factor Receptor (EGF...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Chang, Cheng-Yi, Pan, Ping-Ho, Wu, Chih-Cheng, Liao, Su-Lan, Chen, Wen-Ying, Kuan, Yu-Hsiang, Wang, Wen-Yi, Chen, Chun-Jung
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069544/
https://ncbi.nlm.nih.gov/pubmed/33920356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083934
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