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Endoplasmic Reticulum Stress Contributes to Gefitinib-Induced Apoptosis in Glioma

Adequate stress on the Endoplasmic Reticulum (ER) with the Unfolded Protein Response (UPR) could maintain glioma malignancy. Uncontrolled ER stress, on the other hand, predisposes an apoptosis-dominant UPR program. We studied here the proapoptotic actions of the Epidermal Growth Factor Receptor (EGF...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Chang, Cheng-Yi, Pan, Ping-Ho, Wu, Chih-Cheng, Liao, Su-Lan, Chen, Wen-Ying, Kuan, Yu-Hsiang, Wang, Wen-Yi, Chen, Chun-Jung
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069544/
https://ncbi.nlm.nih.gov/pubmed/33920356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083934
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