Sulindac Sulfide Inhibits Sarcoendoplasmic Reticulum Ca(2+) ATPase, Induces Endoplasmic Reticulum Stress Response, and Exerts Toxicity in Glioma Cells: Relevant Similarities To and Important Differences From Celecoxib

Malignant gliomas have low survival expectations regardless of current treatments. Nonsteroidal anti-inflammatory drugs (NSAIDs) prevent cell transformation and slow cancer cell growth by mechanisms independent of cyclooxygenase (COX) inhibition. Certain NSAIDs trigger the endoplasmic reticulum stre...

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Bibliographische Detailangaben
Hauptverfasser: White, M.C., Johnson, G.G., Zhang, W., Hobrath, J.V., Piazza, G.A., Grimaldi, M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595008/
https://ncbi.nlm.nih.gov/pubmed/23280445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23169
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