Mitochondrial NLRP3 Protein Induces Reactive Oxygen Species to Promote Smad Protein Signaling and Fibrosis Independent from the Inflammasome

Nucleotide-binding domain and leucine-rich repeat containing PYD-3 (NLRP3) is a pattern recognition receptor that is implicated in the pathogenesis of inflammation and chronic diseases. Although much is known regarding the NLRP3 inflammasome that regulates proinflammatory cytokine production in inna...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Bracey, Nathan A., Gershkovich, Benjamin, Chun, Justin, Vilaysane, Akosua, Meijndert, H. Christopher, Wright, James R., Fedak, Paul W., Beck, Paul L., Muruve, Daniel A., Duff, Henry J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2014
Θέματα:
Immunology
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094069/
https://ncbi.nlm.nih.gov/pubmed/24841199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.550624
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