The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

Inflammation significantly contributes to the progression of chronic kidney disease (CKD). Inflammasome-dependent cytokines, such as IL-1β and IL-18, play a role in CKD, but their regulation during renal injury is unknown. Here, we analyzed the processing of caspase-1, IL-1β, and IL-18 after unilate...

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Detalhes bibliográficos
Main Authors: Vilaysane, Akosua, Chun, Justin, Seamone, Mark E., Wang, Wenjie, Chin, Rick, Hirota, Simon, Li, Yan, Clark, Sharon A., Tschopp, Jurg, Trpkov, Kiril, Hemmelgarn, Brenda R., Beck, Paul L., Muruve, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013544/
https://ncbi.nlm.nih.gov/pubmed/20688930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010020143
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