NLRP3 Localizes to the Tubular Epithelium in Human Kidney and Correlates With Outcome in IgA Nephropathy

Nod-like receptor pyrin domain-containing-3 (NLRP3) has been implicated in the pathogenesis of experimental renal injury, yet its characterization in human kidney disease remains largely unexplored. NLRP3 expression was evaluated in human kidney biopsies, primary renal tubular cells (HPTC) and corre...

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Udgivet i:Sci Rep
Main Authors: Chun, Justin, Chung, Hyunjae, Wang, Xiangyu, Barry, Rebecca, Taheri, Zohreh Mohammad, Platnich, Jaye M., Ahmed, Sofia B., Trpkov, Kiril, Hemmelgarn, Brenda, Benediktsson, Hallgrimur, James, Matthew T., Muruve, Daniel A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837396/
https://ncbi.nlm.nih.gov/pubmed/27093923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24667
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