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NLRP3 Localizes to the Tubular Epithelium in Human Kidney and Correlates With Outcome in IgA Nephropathy

Nod-like receptor pyrin domain-containing-3 (NLRP3) has been implicated in the pathogenesis of experimental renal injury, yet its characterization in human kidney disease remains largely unexplored. NLRP3 expression was evaluated in human kidney biopsies, primary renal tubular cells (HPTC) and corre...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chun, Justin, Chung, Hyunjae, Wang, Xiangyu, Barry, Rebecca, Taheri, Zohreh Mohammad, Platnich, Jaye M., Ahmed, Sofia B., Trpkov, Kiril, Hemmelgarn, Brenda, Benediktsson, Hallgrimur, James, Matthew T., Muruve, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837396/
https://ncbi.nlm.nih.gov/pubmed/27093923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24667
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