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NLRP3 Localizes to the Tubular Epithelium in Human Kidney and Correlates With Outcome in IgA Nephropathy

Nod-like receptor pyrin domain-containing-3 (NLRP3) has been implicated in the pathogenesis of experimental renal injury, yet its characterization in human kidney disease remains largely unexplored. NLRP3 expression was evaluated in human kidney biopsies, primary renal tubular cells (HPTC) and corre...

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Publicado en:Sci Rep
Main Authors: Chun, Justin, Chung, Hyunjae, Wang, Xiangyu, Barry, Rebecca, Taheri, Zohreh Mohammad, Platnich, Jaye M., Ahmed, Sofia B., Trpkov, Kiril, Hemmelgarn, Brenda, Benediktsson, Hallgrimur, James, Matthew T., Muruve, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837396/
https://ncbi.nlm.nih.gov/pubmed/27093923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24667
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