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IgA1 deposition may induce NLRP3 expression and macrophage transdifferentiation of podocyte in IgA nephropathy
BACKGROUND: The NLRP3 inflammasome plays an important role in mediating podocyte injury in various kidney diseases. The aim of this study was to investigate whether NLRP3 expression associated with podocyte injury was involved in the pathogenesis of IgA nephropathy (IgAN). METHODS: NLRP3 inflammasom...
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| Publicado no: | J Transl Med |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6891954/ https://ncbi.nlm.nih.gov/pubmed/31796125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02157-2 |
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