Mitochondrial NLRP3 Protein Induces Reactive Oxygen Species to Promote Smad Protein Signaling and Fibrosis Independent from the Inflammasome

Nucleotide-binding domain and leucine-rich repeat containing PYD-3 (NLRP3) is a pattern recognition receptor that is implicated in the pathogenesis of inflammation and chronic diseases. Although much is known regarding the NLRP3 inflammasome that regulates proinflammatory cytokine production in inna...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bracey, Nathan A., Gershkovich, Benjamin, Chun, Justin, Vilaysane, Akosua, Meijndert, H. Christopher, Wright, James R., Fedak, Paul W., Beck, Paul L., Muruve, Daniel A., Duff, Henry J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094069/
https://ncbi.nlm.nih.gov/pubmed/24841199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.550624
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados