Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer

Increasing health care costs in the US are due in a large part to the increasing prevalence of chronic diseases in an aging population. Current therapeutic strategies for treating chronic diseases alleviate symptoms allowing patients to live longer with these diseases, but they do little, however, t...

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Bibliographic Details
Main Authors: Overley-Adamson, Beth, Artlett, Carol M, Stephens, Connie, Sassi-Gaha, Sihem, Weis, Ransome D, Thacker, James D
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979823/
https://ncbi.nlm.nih.gov/pubmed/24496016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27820
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