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Population pharmacokinetics of nefopam in elderly, with or without renal impairment, and its link to treatment response

AIMS: Nefopam is a nonmorphinic central analgesic, for which no recommendation exists concerning adaptation of regimen in aged patients with or without renal impairment. The objective was to describe the pharmacology of nefopam in aged patients to obtain guidelines for practical use. METHODS: Elderl...

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Hlavní autoři: Djerada, Zoubir, Fournet-Fayard, Aurélie, Gozalo, Claire, Lelarge, Chantal, Lamiable, Denis, Millart, Hervé, Malinovsky, Jean-Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093928/
https://ncbi.nlm.nih.gov/pubmed/24252055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12291
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