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Pharmacokinetics of brotizolam in the elderly

1 Disposition of brotizolam in patients aged 71-93 years was compared with that of healthy young subjects aged 21-26 years. 2 The mean elimination half-life of brotizolam was about twice as long in the elderly as in the young subjects: 9.3 (4.0-19.5) h and 4.8 (3.1-6.3) h respectively. Increase in e...

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Detalhes bibliográficos
Main Authors: Jochemsen, Roeline, Nandi, K. L., Corless, D., Wesselman, J. G. J., Breimer, D. D.
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1428236/
https://ncbi.nlm.nih.gov/pubmed/6661375
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