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Pharmacokinetics of brotizolam in healthy subjects following intravenous and oral administration

1 Pharmacokinetics and bioavailability of brotizolam after i.v. and oral administration were studied in healthy young volunteers. 2 Kinetic parameters after i.v. administration were: volume of distribution 0.66 ± 0.19 1/kg, total plasma clearance 113 ± 28 ml/min, distribution half-life 11 ± 6 min, a...

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Bibliografische gegevens
Hoofdauteurs: Jochemsen, Roeline, Wesselman, J. G. J., Hermans, J., van Boxtel, C. J., Breimer, D. D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1983
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1428208/
https://ncbi.nlm.nih.gov/pubmed/6661374
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