Pharmacokinetics and concentration–effect relationship of adalimumab in rheumatoid arthritis

AIMS: This study aimed at describing adalimumab pharmacokinetics (PK) and the concentration–effect relationship of adalimumab using pharmacokinetic–pharmacodynamic (PK–PD) modelling in patients with rheumatoid arthritis (RA). METHODS: Adalimumab PK and PK–PD data were obtained from a multicentric ob...

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Detalles Bibliográficos
Publicado en:Br J Clin Pharmacol
Main Authors: Ternant, David, Ducourau, Emilie, Fuzibet, Piéra, Vignault, Céline, Watier, Hervé, Lequerré, Thierry, Le Loët, Xavier, Vittecoq, Olivier, Goupille, Philippe, Mulleman, Denis, Paintaud, Gilles
Formato: Artigo
Idioma:Inglês
Publicado: BlackWell Publishing Ltd 2015
Assuntos:
Pharmacokinetic Dynamic Relationships
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309634/
https://ncbi.nlm.nih.gov/pubmed/25223394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12509
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