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Infliximab in ankylosing spondylitis: alone or in combination with methotrexate? A pharmacokinetic comparative study

INTRODUCTION: Methotrexate (MTX) has been shown to modify infliximab pharmacokinetics in rheumatoid arthritis. However, its combination with infliximab in the treatment of ankylosing spondylitis (AS) is not recommended. The objective of this study was to examine the influence of MTX on infliximab ex...

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Autors principals: Mulleman, Denis, Lauféron, Francine, Wendling, Daniel, Ternant, David, Ducourau, Emilie, Paintaud, Gilles, Goupille, Philippe
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218893/
https://ncbi.nlm.nih.gov/pubmed/21639907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3350
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