Relationship between inflammation and infliximab pharmacokinetics in rheumatoid arthritis

AIMS: Infliximab, an anti-tumour necrosis factor-α monoclonal antibody, is indicated in rheumatoid arthritis (RA). Our objective was to evaluate the influence of the sources of infliximab pharmacokinetic variability in RA. METHODS: Eighty-four patients treated with infliximab for RA were included in...

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Detalhes bibliográficos
Main Authors: Ternant, David, Ducourau, Emilie, Perdriger, Aleth, Corondan, Anca, Le Goff, Benoît, Devauchelle-Pensec, Valérie, Solau-Gervais, Elisabeth, Watier, Hervé, Goupille, Philippe, Paintaud, Gilles, Mulleman, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Pharmacokinetic Dynamic Relationships
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168386/
https://ncbi.nlm.nih.gov/pubmed/24354889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12313
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