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Influence of methotrexate on infliximab pharmacokinetics and pharmacodynamics in ankylosing spondylitis

AIMS: Infliximab, an anti-tumour necrosis factor α monoclonal antibody, has profoundly modified the treatment of several inflammatory diseases. The objective was to assess the influence of methotrexate on the variability of infliximab pharmacokinetics and concentration–effect relationship in axial a...

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Detalhes bibliográficos
Main Authors: Ternant, David, Mulleman, Denis, Lauféron, Francine, Vignault, Céline, Ducourau, Emilie, Wendling, Daniel, Goupille, Philippe, Paintaud, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248256/
https://ncbi.nlm.nih.gov/pubmed/21692827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04050.x
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