Mitochondrial-nuclear genome interactions in nonalcoholic fatty liver disease in mice

Nonalcoholic fatty liver disease (NAFLD) involves significant changes in liver metabolism characterized by oxidative stress, lipid accumulation, and fibrogenesis. Mitochondrial dysfunction and bioenergetic defects also contribute to NAFLD. Herein, we examined whether differences in mtDNA influence N...

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Bibliographische Detailangaben
Hauptverfasser: Betancourt, Angela M., King, Adrienne L., Fetterman, Jessica L., Millender-Swain, Telisha, Finley, Rachel D., Oliva, Claudia R., Crowe, David Ralph, Ballinger, Scott W., Bailey, Shannon M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086355/
https://ncbi.nlm.nih.gov/pubmed/24758559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131433
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