The methyl donor S-adenosylmethionine prevents liver hypoxia and dysregulation of mitochondrial bioenergetic function in a rat model of alcohol-induced fatty liver disease

BACKGROUND: Mitochondrial dysfunction and bioenergetic stress play an important role in the etiology of alcoholic liver disease. Previous studies from our laboratory show that the primary methyl donor S-Adenosylmethionine (SAM) minimizes alcohol-induced disruptions in several mitochondrial functions...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Redox Biol
Prif Awduron: King, Adrienne L., Mantena, Sudheer K., Andringa, Kelly K., Millender-Swain, Telisha, Dunham-Snary, Kimberly J., Oliva, Claudia R., Griguer, Corinne E., Bailey, Shannon M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007436/
https://ncbi.nlm.nih.gov/pubmed/27566282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.08.005
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