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Mitochondrial Dysfunction and Oxidative Stress in the Pathogenesis of Alcohol and Obesity Induced Fatty Liver Diseases

Fatty liver disease associated with chronic alcohol consumption or obesity/type 2 diabetes has emerged as a serious public health problem. Steatosis, accumulation of triglyceride in hepatocytes, is now recognized as a critical “first-hit” in the pathogenesis of liver disease. It is proposed that ste...

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Detalhes bibliográficos
Main Authors: Mantena, Sudheer K., King, Adrienne L., Andringa, Kelly K., Eccleston, Heather B., Bailey, Shannon M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323912/
https://ncbi.nlm.nih.gov/pubmed/18242193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.12.029
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