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Mitochondrial-nuclear genome interactions in nonalcoholic fatty liver disease in mice

Nonalcoholic fatty liver disease (NAFLD) involves significant changes in liver metabolism characterized by oxidative stress, lipid accumulation, and fibrogenesis. Mitochondrial dysfunction and bioenergetic defects also contribute to NAFLD. Herein, we examined whether differences in mtDNA influence N...

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主要な著者: Betancourt, Angela M., King, Adrienne L., Fetterman, Jessica L., Millender-Swain, Telisha, Finley, Rachel D., Oliva, Claudia R., Crowe, David Ralph, Ballinger, Scott W., Bailey, Shannon M.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086355/
https://ncbi.nlm.nih.gov/pubmed/24758559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131433
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