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Mitochondrial-nuclear genome interactions in nonalcoholic fatty liver disease in mice

Nonalcoholic fatty liver disease (NAFLD) involves significant changes in liver metabolism characterized by oxidative stress, lipid accumulation, and fibrogenesis. Mitochondrial dysfunction and bioenergetic defects also contribute to NAFLD. Herein, we examined whether differences in mtDNA influence N...

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Detalhes bibliográficos
Main Authors: Betancourt, Angela M., King, Adrienne L., Fetterman, Jessica L., Millender-Swain, Telisha, Finley, Rachel D., Oliva, Claudia R., Crowe, David Ralph, Ballinger, Scott W., Bailey, Shannon M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086355/
https://ncbi.nlm.nih.gov/pubmed/24758559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131433
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