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Mitochondrial-nuclear genome interactions in nonalcoholic fatty liver disease in mice

Nonalcoholic fatty liver disease (NAFLD) involves significant changes in liver metabolism characterized by oxidative stress, lipid accumulation, and fibrogenesis. Mitochondrial dysfunction and bioenergetic defects also contribute to NAFLD. Herein, we examined whether differences in mtDNA influence N...

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Hlavní autoři: Betancourt, Angela M., King, Adrienne L., Fetterman, Jessica L., Millender-Swain, Telisha, Finley, Rachel D., Oliva, Claudia R., Crowe, David Ralph, Ballinger, Scott W., Bailey, Shannon M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086355/
https://ncbi.nlm.nih.gov/pubmed/24758559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131433
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