Variation in the Circumsporozoite Protein of Plasmodium falciparum: Vaccine Development Implications

The malaria vaccine candidate RTS,S/AS01 is based on immunogenic regions of Plasmodium falciparum circumsporozoite protein (CSP) from the 3D7 reference strain and has shown modest efficacy against clinical disease in African children. It remains unclear what aspect(s) of the immune response elicited...

詳細記述

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書誌詳細
主要な著者: Gandhi, Kavita, Thera, Mahamadou A., Coulibaly, Drissa, Traoré, Karim, Guindo, Ando B., Ouattara, Amed, Takala-Harrison, Shannon, Berry, Andrea A., Doumbo, Ogobara K., Plowe, Christopher V.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081809/
https://ncbi.nlm.nih.gov/pubmed/24992338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101783
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