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Variation in the Circumsporozoite Protein of Plasmodium falciparum: Vaccine Development Implications
The malaria vaccine candidate RTS,S/AS01 is based on immunogenic regions of Plasmodium falciparum circumsporozoite protein (CSP) from the 3D7 reference strain and has shown modest efficacy against clinical disease in African children. It remains unclear what aspect(s) of the immune response elicited...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081809/ https://ncbi.nlm.nih.gov/pubmed/24992338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101783 |
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