Variation in the Circumsporozoite Protein of Plasmodium falciparum: Vaccine Development Implications

The malaria vaccine candidate RTS,S/AS01 is based on immunogenic regions of Plasmodium falciparum circumsporozoite protein (CSP) from the 3D7 reference strain and has shown modest efficacy against clinical disease in African children. It remains unclear what aspect(s) of the immune response elicited...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Gandhi, Kavita, Thera, Mahamadou A., Coulibaly, Drissa, Traoré, Karim, Guindo, Ando B., Ouattara, Amed, Takala-Harrison, Shannon, Berry, Andrea A., Doumbo, Ogobara K., Plowe, Christopher V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081809/
https://ncbi.nlm.nih.gov/pubmed/24992338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101783
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