A high-throughput method for quantifying alleles and haplotypes of the malaria vaccine candidate Plasmodium falciparum merozoite surface protein-1 19 kDa

BACKGROUND: Malaria vaccine efficacy may be compromised if the frequency of non-target alleles increases following vaccination with a genetically polymorphic target. Methods are needed to monitor genetic diversity in polymorphic vaccine antigens, but determining which genetic variants of such antige...

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Bibliografske podrobnosti
Main Authors: Takala, Shannon L, Smith, David L, Stine, O Colin, Coulibaly, Drissa, Thera, Mahamadou A, Doumbo, Ogobara K, Plowe, Christopher V
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2006
Teme:
Methodology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459863/
https://ncbi.nlm.nih.gov/pubmed/16626494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-5-31
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