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Inhibition of the 4Fe-4S Proteins IspG and IspH: an EPR, ENDOR and HYSCORE Investigation
IspG and IspH are proteins that are involved in isoprenoid biosynthesis in most bacteria as well as in malaria parasites and are important drug targets. They contain cubane-type 4Fe-4S clusters that are involved in unusual 2H(+)/2e(−) reductions. Here, we report the results of electron paramagnetic...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4078884/ https://ncbi.nlm.nih.gov/pubmed/24999381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3SC53301H |
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