Laddar...

Bioorganometallic Chemistry with IspG and IspH: Structure, Function and Inhibition of the [Fe(4)S(4)] Proteins Involved in Isoprenoid Biosynthesis

The methylerythritol phosphate pathway of isoprenoid biosynthesis is an attractive anti-infective drug target. The last two enzymes of this pathway, IspG and IspH, are [Fe(4)S(4)] proteins not produced by humans that catalyze 2H(+)/2e(−) reductions with novel mechanisms. In this review, we summarize...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Wang, Weixue, Oldfield, Eric
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997630/
https://ncbi.nlm.nih.gov/pubmed/24481599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201306712
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!