Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the α cardiac myosin heavy chain gene
Heterozygous mice bearing an Arg403Gln missense mutation in the α cardiac myosin heavy chain gene (α-MHC(403/+)) exhibit the histopathologic features of human familial hypertrophic cardiomyopathy. Surprisingly, homozygous α-MHC(403/403) mice die by postnatal day 8. Here we report that neonatal letha...
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| Yayımlandı: | J Clin Invest |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
1999
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC407864/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9884344/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI4631 |
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