The cardiac myosin heavy chain Arg-403-->Gln mutation that causes hypertrophic cardiomyopathy does not affect the actin- or ATP-binding capacities of two size-limited recombinant myosin heavy chain fragments.

Ítems similars

• Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the α cardiac myosin heavy chain gene
  per: Fatkin, Diane, et al.
  Publicat: (1999)
• Cell-Intrinsic Functional Effects of the α-Cardiac Myosin Arg-403-Gln Mutation in Familial Hypertrophic Cardiomyopathy
  per: Chuan, Peiying, et al.
  Publicat: (2012)
• Development of induced pluripotent stem cells from a patient with hypertrophic cardiomyopathy who carries the pathogenic myosin heavy chain 7 mutation p.Arg403Gln
  per: Mira Holliday, et al.
  Publicat: (2018-12-01)
• Functional Effects of the Hypertrophic Cardiomyopathy R403Q Mutation Are Different in an α- or β-Myosin Heavy Chain Backbone
  per: Lowey, Susan, et al.
  Publicat: (2008)
• Loss or Gain: Myosin Heavy Chain Truncations in Hypertrophic Cardiomyopathy
  per: Soumojit Pal, et al.
  Publicat: (2025-11-01)