Aggregation Behavior of Chemically Synthesized, Full-Length Huntingtin Exon1

[Image: see text] Repeat length disease thresholds vary among the 10 expanded polyglutamine (polyQ) repeat diseases, from about 20 to about 50 glutamine residues. The unique amino acid sequences flanking the polyQ segment are thought to contribute to these repeat length thresholds. The specific port...

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Hlavní autoři: Sahoo, Bankanidhi, Singer, David, Kodali, Ravindra, Zuchner, Thole, Wetzel, Ronald
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075985/
https://ncbi.nlm.nih.gov/pubmed/24921664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500300c
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