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Critical nucleus size for disease-related polyglutamine aggregation is repeat length dependent
Since polyglutamine (polyQ) aggregate formation has been implicated as playing an important role in expanded CAG repeat diseases, it is important to understand the biophysics underlying the initiation of aggregation. Previously we showed that relatively long polyQ peptides aggregate by nucleated gro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075957/ https://ncbi.nlm.nih.gov/pubmed/21317897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1992 |
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