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Aggregation Behavior of Chemically Synthesized, Full-Length Huntingtin Exon1
[Image: see text] Repeat length disease thresholds vary among the 10 expanded polyglutamine (polyQ) repeat diseases, from about 20 to about 50 glutamine residues. The unique amino acid sequences flanking the polyQ segment are thought to contribute to these repeat length thresholds. The specific port...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American
Chemical Society
2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4075985/ https://ncbi.nlm.nih.gov/pubmed/24921664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500300c |
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