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Assays for studying nucleated aggregation of polyglutamine proteins
The aggregation of polyglutamine containing protein sequences is implicated in a family of familial neurodegenerative diseases, the expanded CAG repeat diseases. While the cellular aggregation process undoubtedly depends on the flux and local environment of these proteins, their intrinsic physical p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057327/ https://ncbi.nlm.nih.gov/pubmed/21232603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2011.01.001 |
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