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Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans

For each round of pre-mRNA splicing, a spliceosome is assembled anew on its substrate. RNA–protein remodeling events required for spliceosome assembly, splicing catalysis, and spliceosome disassembly are driven and controlled by a conserved group of ATPases/RNA helicases. The activities of most of t...

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Detalhes bibliográficos
Main Authors: Mozaffari-Jovin, Sina, Wandersleben, Traudy, Santos, Karine F, Will, Cindy L, Lührmann, Reinhard, Wahl, Markus C
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075514/
https://ncbi.nlm.nih.gov/pubmed/24643059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.28353
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