Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2

RNA helicase Brr2 is implicated in multiple phases of pre-mRNA splicing and thus requires tight regulation. Brr2 can be auto-inhibited via a large N-terminal region folding back onto its helicase core and auto-activated by a catalytically inactive C-terminal helicase cassette. Furthermore, it can be...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Cycle
Egile Nagusiak: Absmeier, Eva, Becke, Christian, Wollenhaupt, Jan, Santos, Karine F., Wahl, Markus C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2016
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270545/
https://ncbi.nlm.nih.gov/pubmed/27880071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1255384
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