Cell autonomous regulation of hippocampal circuitry via Aph1b-γ-secretase/neuregulin 1 signalling

Neuregulin 1 (NRG1) and the γ-secretase subunit APH1B have been previously implicated as genetic risk factors for schizophrenia and schizophrenia relevant deficits have been observed in rodent models with loss of function mutations in either gene. Here we show that the Aph1b-γ-secretase is selective...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Fazzari, Pietro, Snellinx, An, Sabanov, Victor, Ahmed, Tariq, Serneels, Lutgarde, Gartner, Annette, Shariati, S Ali M, Balschun, Detlef, De Strooper, Bart
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2014
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073283/
https://ncbi.nlm.nih.gov/pubmed/24891237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02196
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars