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Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 2. Colistin

The purpose of this study was to investigate the pharmacokinetic properties of colistin following intrapulmonary administration of colistin sulfate in rats. Colistin was infused or delivered in nebulized form at a dose of 0.35 mg/kg of body weight in rats, and plasma drug concentrations were measure...

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Bibliografiske detaljer
Main Authors: Gontijo, Aline Vidal Lacerda, Grégoire, Nicolas, Lamarche, Isabelle, Gobin, Patrice, Couet, William, Marchand, Sandrine
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068596/
https://ncbi.nlm.nih.gov/pubmed/24798284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02819-14
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