Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 1. Ciprofloxacin, Moxifloxacin, and Grepafloxacin

The aim of this study was to evaluate the biopharmaceutical characteristics of three fluoroquinolones (FQs), ciprofloxacin (CIP), moxifloxacin (MXF), and grepafloxacin (GRX), after delivery via a nebulized aerosol to rats. Bronchoalveolar lavages (BAL) were conducted 0.5, 2, 4, and 6 h after FQ intr...

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Bibliographic Details
Main Authors: Gontijo, Aline Vidal Lacerda, Brillault, Julien, Grégoire, Nicolas, Lamarche, Isabelle, Gobin, Patrice, Couet, William, Marchand, Sandrine
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068515/
https://ncbi.nlm.nih.gov/pubmed/24798283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02818-14
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