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Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 3. Tobramycin

The aim of this study was to determine the biopharmaceutical characteristics of tobramycin (TOB) after nebulization in rats. TOB was administered by intravenous (i.v.) bolus or intratracheal nebulization (3 mg · kg(−1)), and concentrations were determined in plasma and epithelial lining fluid (ELF)...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Marchand, Sandrine, Grégoire, Nicolas, Brillault, Julien, Lamarche, Isabelle, Gobin, Patrice, Couet, William
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576081/
https://ncbi.nlm.nih.gov/pubmed/26239992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01647-15
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