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Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 3. Tobramycin
The aim of this study was to determine the biopharmaceutical characteristics of tobramycin (TOB) after nebulization in rats. TOB was administered by intravenous (i.v.) bolus or intratracheal nebulization (3 mg · kg(−1)), and concentrations were determined in plasma and epithelial lining fluid (ELF)...
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| Publicat a: | Antimicrob Agents Chemother |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4576081/ https://ncbi.nlm.nih.gov/pubmed/26239992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01647-15 |
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