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Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 3. Tobramycin

The aim of this study was to determine the biopharmaceutical characteristics of tobramycin (TOB) after nebulization in rats. TOB was administered by intravenous (i.v.) bolus or intratracheal nebulization (3 mg · kg(−1)), and concentrations were determined in plasma and epithelial lining fluid (ELF)...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Marchand, Sandrine, Grégoire, Nicolas, Brillault, Julien, Lamarche, Isabelle, Gobin, Patrice, Couet, William
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576081/
https://ncbi.nlm.nih.gov/pubmed/26239992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01647-15
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