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Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 5. Oseltamivir Carboxylate

The aim of this study was to determine the biopharmaceutical characteristics of oseltamivir carboxylate (OC) after pulmonary delivery. After OC bolus and intratracheal nebulization (NEB) in rats, blood was collected and bronchoalveolar lavages (BALs) were performed. Epithelial lining fluid (ELF) con...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Galindo Bedor, Danilo Cesar, Marchand, Sandrine, Lamarche, Isabelle, Laroche, Julian, Pereira de Santana, Davi, Couet, William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958211/
https://ncbi.nlm.nih.gov/pubmed/27297482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00909-16
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